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Effect of H(2)S on the circadian rhythm of mouse hepatocytes

BACKGROUND: Dysregulation of circadian rhythms can contribute to diseases of lipid metabolism. NAD-dependent deacetylase sirtuin-1(SIRT1) is an important hub which links lipid metabolism with circadian clock by its deacetylation activity depends on intracellular NAD(+)/NADH content ratio. Hydrogen s...

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Detalles Bibliográficos
Autores principales: Shang, Zhanxian, Lu, Chao, Chen, Sifeng, Hua, Luchun, Qian, Ruizhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292508/
https://www.ncbi.nlm.nih.gov/pubmed/22316301
http://dx.doi.org/10.1186/1476-511X-11-23