Cargando…

Inhibition of STAT3 signaling and induction of SHP1 mediate antiangiogenic and antitumor activities of ergosterol peroxide in U266 multiple myeloma cells

BACKGROUND: Ergosterol peroxide (EP) derived from edible mushroom has been shown to exert anti-tumor activity in several cancer cells. In the present study, anti-angiogenic activity of EP was investigated with the underlying molecular mechanisms in human multiple myeloma U266 cells. RESULTS: Despite...

Descripción completa

Detalles Bibliográficos
Autores principales: Rhee, Yun-Hee, Jeong, Soo-Jin, Lee, Hyo-Jeong, Lee, Hyo-Jung, Koh, Wonil, Jung, Ji Hoon, Kim, Sun-Hee, Sung-Hoon, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292511/
https://www.ncbi.nlm.nih.gov/pubmed/22260501
http://dx.doi.org/10.1186/1471-2407-12-28