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Inhibition of STAT3 signaling and induction of SHP1 mediate antiangiogenic and antitumor activities of ergosterol peroxide in U266 multiple myeloma cells
BACKGROUND: Ergosterol peroxide (EP) derived from edible mushroom has been shown to exert anti-tumor activity in several cancer cells. In the present study, anti-angiogenic activity of EP was investigated with the underlying molecular mechanisms in human multiple myeloma U266 cells. RESULTS: Despite...
Autores principales: | Rhee, Yun-Hee, Jeong, Soo-Jin, Lee, Hyo-Jeong, Lee, Hyo-Jung, Koh, Wonil, Jung, Ji Hoon, Kim, Sun-Hee, Sung-Hoon, Kim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292511/ https://www.ncbi.nlm.nih.gov/pubmed/22260501 http://dx.doi.org/10.1186/1471-2407-12-28 |
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