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CSF Concentrations of cAMP and cGMP Are Lower in Patients with Creutzfeldt-Jakob Disease but Not Parkinson's Disease and Amyotrophic Lateral Sclerosis

BACKGROUND: The cyclic nucleotides cyclic adenosine-3′,5′-monophosphate (cAMP) and cyclic guanosine-3′,5′-monophosphate (cGMP) are important second messengers and are potential biomarkers for Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and Creutzfeldt-Jakob disease (CJD). METH...

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Detalles Bibliográficos
Autores principales: Oeckl, Patrick, Steinacker, Petra, Lehnert, Stefan, Jesse, Sarah, Kretzschmar, Hans A., Ludolph, Albert C., Otto, Markus, Ferger, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292568/
https://www.ncbi.nlm.nih.gov/pubmed/22396786
http://dx.doi.org/10.1371/journal.pone.0032664