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Dissociating Markers of Senescence and Protective Ability in Memory T Cells

No unique transcription factor or biomarker has been identified to reliably distinguish effector from memory T cells. Instead a set of surface markers including IL-7Rα and KLRG1 is commonly used to predict the potential of CD8 effector T cells to differentiate into memory cells. Similarly, these sur...

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Detalles Bibliográficos
Autores principales: Prlic, Martin, Sacks, Jilian A., Bevan, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292574/
https://www.ncbi.nlm.nih.gov/pubmed/22396780
http://dx.doi.org/10.1371/journal.pone.0032576