Cargando…

Efficient in vitro RNA interference and immunofluorescence-based phenotype analysis in a human parasitic nematode, Brugia malayi

BACKGROUND: RNA interference (RNAi) is an efficient reverse genetics technique for investigating gene function in eukaryotes. The method has been widely used in model organisms, such as the free-living nematode Caenorhabditis elegans, where it has been deployed in genome-wide high throughput screens...

Descripción completa

Detalles Bibliográficos
Autores principales:	Landmann, Frédéric, Foster, Jeremy M, Slatko, Barton E, Sullivan, William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292814/ https://www.ncbi.nlm.nih.gov/pubmed/22243803 http://dx.doi.org/10.1186/1756-3305-5-16

Ejemplares similares

Characterization of innate immunity genes in the parasitic nematode Brugia malayi
por: Libro, Silvia, et al.
Publicado: (2016)

Heme acquisition in the parasitic filarial nematode Brugia malayi
por: Luck, Ashley N., et al.
Publicado: (2016)

Asymmetric Wolbachia Segregation during Early Brugia malayi Embryogenesis Determines Its Distribution in Adult Host Tissues
por: Landmann, Frédéric, et al.
Publicado: (2010)

Defining the filarial N-glycoproteome by glycosite mapping in the human parasitic nematode Brugia malayi
por: Mersha, Fana B., et al.
Publicado: (2023)

Computational and experimental analysis of the glycophosphatidylinositol-anchored proteome of the human parasitic nematode Brugia malayi
por: Mersha, Fana B., et al.
Publicado: (2019)

The Wolbachia Genome of Brugia malayi: Endosymbiont Evolution within a Human Pathogenic Nematode
por: Foster, Jeremy, et al.
Publicado: (2005)

Mining Predicted Essential Genes of Brugia malayi for Nematode Drug Targets
por: Kumar, Sanjay, et al.
Publicado: (2007)

Alteration of rhesus macaque serum N-glycome during infection with the human parasitic filarial nematode Brugia malayi
por: Petralia, Laudine M. C., et al.
Publicado: (2022)

The Heme Biosynthetic Pathway of the Obligate Wolbachia Endosymbiont of Brugia malayi as a Potential Anti-filarial Drug Target
por: Wu, Bo, et al.
Publicado: (2009)

Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus
por: Fata, Francesca, et al.
Publicado: (2022)

Answer: Microfilaria of Brugia malayi
por: Khurana, Vishal, et al.
Publicado: (2014)

Diversity and Expression of MicroRNAs in the Filarial Parasite, Brugia malayi
por: Poole, Catherine B., et al.
Publicado: (2014)

In vitro flubendazole-induced damage to vital tissues in adult females of the filarial nematode Brugia malayi
por: O'Neill, Maeghan, et al.
Publicado: (2015)

Prolyl 4-Hydroxlase Activity Is Essential for Development and Cuticle Formation in the Human Infective Parasitic Nematode Brugia malayi
por: Winter, Alan D., et al.
Publicado: (2013)

Intraperitoneal development of the filarial nematode Brugia malayi in the Mongolian jird (Meriones unguiculatus)
por: Mutafchiev, Yasen, et al.
Publicado: (2014)

The Effect of In Vitro Cultivation on the Transcriptome of Adult Brugia malayi
por: Ballesteros, Cristina, et al.
Publicado: (2016)

CRISPR-mediated Transfection of Brugia malayi
por: Liu, Canhui, et al.
Publicado: (2020)

In vivo imaging of transgenic Brugia malayi
por: Liu, Canhui, et al.
Publicado: (2020)

Chitinase is stored and secreted from the inner body of microfilariae and has a role in exsheathment in the parasitic nematode Brugia malayi
por: Wu, Yang, et al.
Publicado: (2008)

Differential transcript expression between the microfilariae of the filarial nematodes, Brugia malayi and B. pahangi
por: Kariuki, Michael M, et al.
Publicado: (2010)

Development of an In Vivo RNAi Protocol to Investigate Gene Function in the Filarial Nematode, Brugia malayi
por: Song, Chuanzhe, et al.
Publicado: (2010)

In vitro gene silencing of independent phosphoglycerate mutase (iPGM) in the filarial parasite Brugia malayi
por: Singh, Prashant Kumar, et al.
Publicado: (2013)

Dual RNAseq analyses at soma and germline levels reveal evolutionary innovations in the elephantiasis-agent Brugia malayi, and adaptation of its Wolbachia endosymbionts
por: Chevignon, Germain, et al.
Publicado: (2021)

Michael Adduct of Sulfonamide Chalcone Targets Folate Metabolism in Brugia Malayi Parasite
por: Bhoj, Priyanka S., et al.
Publicado: (2023)

Co-evolution between an Endosymbiont and Its Nematode Host: Wolbachia Asymmetric Posterior Localization and AP Polarity Establishment
por: Landmann, Frederic, et al.
Publicado: (2014)

Anthelmintic resistance and homeostatic plasticity (Brugia malayi)
por: Kashyap, Sudhanva S., et al.
Publicado: (2021)

Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi
por: Li, Ben-Wen, et al.
Publicado: (2012)

Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi
por: Holman, Alexander G, et al.
Publicado: (2009)

In Vitro Activity of Geldanamycin Derivatives against Schistosoma japonicum and Brugia malayi
por: Wenkert, David, et al.
Publicado: (2010)

The Effects of Ivermectin on Brugia malayi Females In Vitro: A Transcriptomic Approach
por: Ballesteros, Cristina, et al.
Publicado: (2016)

Mass Spectrometric and Glycan Microarray–Based Characterization of the Filarial Nematode Brugia malayi Glycome Reveals Anionic and Zwitterionic Glycan Antigens
por: Petralia, Laudine M.C., et al.
Publicado: (2022)

The Annotated Genome of Wolbachia from the Filarial Nematode Brugia malayi: What It Means for Progress in Antifilarial Medicine
por: Pfarr, Kenneth, et al.
Publicado: (2005)

Tissue and Stage-Specific Distribution of Wolbachia in Brugia malayi
por: Fischer, Kerstin, et al.
Publicado: (2011)

The Domestic Dog as a Laboratory Host for Brugia malayi
por: Evans, Christopher C., et al.
Publicado: (2022)

Nearly Complete Genome Sequence of Brugia malayi Strain FR3
por: Tracey, Alan, et al.
Publicado: (2020)

Spatial transcriptomics reveals antiparasitic targets associated with essential behaviors in the human parasite Brugia malayi
por: Airs, Paul M., et al.
Publicado: (2022)

Functional Analysis of the Cathepsin-Like Cysteine Protease Genes in Adult Brugia malayi Using RNA Interference
por: Ford, Louise, et al.
Publicado: (2009)

RNA interference mediated knockdown of Brugia malayi UDP-Galactopyranose mutase severely affects parasite viability, embryogenesis and in vivo development of infective larvae
por: Misra, Sweta, et al.
Publicado: (2017)

Absence of Wolbachia endobacteria in the human parasitic nematode Dracunculus medinensis and two related Dracunculus species infecting wildlife
por: Foster, Jeremy M, et al.
Publicado: (2014)

Antibody responses to Brugia malayi antigens induced by DNA vaccination
por: Li, Ben-Wen, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_g9r3hckig62ko1a9dn7kiq1e0f