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Mechanism and Regulation of Nucleocytoplasmic Trafficking of Smad
Smad proteins are the intracellular mediators of transforming growth factor β (TGF-β) signaling. Smads function as transcription factors and their activities require carboxyl-terminal phosphorylation by TGF-β receptor kinases which are embedded in the cell membrane. Therefore, the translocation of a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292837/ https://www.ncbi.nlm.nih.gov/pubmed/22204445 http://dx.doi.org/10.1186/2045-3701-1-40 |