Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice

Calorie restriction results in leanness, which is linked to metabolic conditions that favor longevity. We show here that deficiency of the triglyceride synthesis enzyme acyl CoA:diacylglycerol acyltransferase 1 (DGAT1), which promotes leanness, also extends longevity without limiting food intake. Fe...

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Detalles Bibliográficos
Autores principales: Streeper, Ryan S., Grueter, Carrie A., Salomonis, Nathan, Cases, Sylvaine, Levin, Malin C., Koliwad, Suneil K., Zhou, Ping, Hirschey, Matthew D., Verdin, Eric, Farese, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292902/
https://www.ncbi.nlm.nih.gov/pubmed/22291164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292902/
https://www.ncbi.nlm.nih.gov/pubmed/22291164

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