Cargando…
Concurrent hypermethylation of DNMT1, MGMT and EGFR genes in progression of gliomas
BACKGROUND: Gliomas are the most common neoplasm of the brain. High-grade gliomas often resist treatment even with aggressive surgical resection and adjuvant radiation and chemotherapy. Despite the combined treatment, they frequently recur with the same or higher-grade histology. Genetic instability...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292961/ https://www.ncbi.nlm.nih.gov/pubmed/22264301 http://dx.doi.org/10.1186/1746-1596-7-8 |