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Concurrent hypermethylation of DNMT1, MGMT and EGFR genes in progression of gliomas

BACKGROUND: Gliomas are the most common neoplasm of the brain. High-grade gliomas often resist treatment even with aggressive surgical resection and adjuvant radiation and chemotherapy. Despite the combined treatment, they frequently recur with the same or higher-grade histology. Genetic instability...

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Detalles Bibliográficos
Autores principales:	Gömöri, Éva, Pál, József, Kovács, Bernadett, Dóczi, Tamás
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292961/ https://www.ncbi.nlm.nih.gov/pubmed/22264301 http://dx.doi.org/10.1186/1746-1596-7-8

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