D-Lactate altered mitochondrial energy production in rat brain and heart but not liver

BACKGROUND: Substantially elevated blood D-lactate (DLA) concentrations are associated with neurocardiac toxicity in humans and animals. The neurological symptoms are similar to inherited or acquired abnormalities of pyruvate metabolism. We hypothesized that DLA interferes with mitochondrial utiliza...

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Detalles Bibliográficos
Autores principales: Ling, Binbing, Peng, Fei, Alcorn, Jane, Lohmann, Katharina, Bandy, Brian, Zello, Gordon A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292964/
https://www.ncbi.nlm.nih.gov/pubmed/22296683
http://dx.doi.org/10.1186/1743-7075-9-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292964/
https://www.ncbi.nlm.nih.gov/pubmed/22296683
http://dx.doi.org/10.1186/1743-7075-9-6

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