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D-Lactate altered mitochondrial energy production in rat brain and heart but not liver
BACKGROUND: Substantially elevated blood D-lactate (DLA) concentrations are associated with neurocardiac toxicity in humans and animals. The neurological symptoms are similar to inherited or acquired abnormalities of pyruvate metabolism. We hypothesized that DLA interferes with mitochondrial utiliza...
Autores principales: | Ling, Binbing, Peng, Fei, Alcorn, Jane, Lohmann, Katharina, Bandy, Brian, Zello, Gordon A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292964/ https://www.ncbi.nlm.nih.gov/pubmed/22296683 http://dx.doi.org/10.1186/1743-7075-9-6 |
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