Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα

BACKGROUND: The p38α MAPK isoform is a well-established therapeutic target in peripheral inflammatory diseases, but the importance of this kinase in pathological microglial activation and detrimental inflammation in CNS disorders is less well understood. To test the role of the p38α MAPK isoform in...

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Detalles Bibliográficos
Autores principales: Xing, Bin, Bachstetter, Adam D, Van Eldik, Linda J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292986/
https://www.ncbi.nlm.nih.gov/pubmed/22185458
http://dx.doi.org/10.1186/1750-1326-6-84

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292986/
https://www.ncbi.nlm.nih.gov/pubmed/22185458
http://dx.doi.org/10.1186/1750-1326-6-84

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