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Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα
BACKGROUND: The p38α MAPK isoform is a well-established therapeutic target in peripheral inflammatory diseases, but the importance of this kinase in pathological microglial activation and detrimental inflammation in CNS disorders is less well understood. To test the role of the p38α MAPK isoform in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292986/ https://www.ncbi.nlm.nih.gov/pubmed/22185458 http://dx.doi.org/10.1186/1750-1326-6-84 |