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Non-degradative ubiquitination in Smad-dependent TGF-β signaling
Transforming growth factor-β (TGF-β) signaling is tightly regulated at the level of post-translational modification to transmit quantitative difference in ligand concentration into proportional transcriptional output. Ubiquitination is one such modification with several E3 ubiquitin ligases implicat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293007/ https://www.ncbi.nlm.nih.gov/pubmed/22204598 http://dx.doi.org/10.1186/2045-3701-1-43 |