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Non-degradative ubiquitination in Smad-dependent TGF-β signaling

Transforming growth factor-β (TGF-β) signaling is tightly regulated at the level of post-translational modification to transmit quantitative difference in ligand concentration into proportional transcriptional output. Ubiquitination is one such modification with several E3 ubiquitin ligases implicat...

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Detalles Bibliográficos
Autores principales: Tang, Liu-Ya, Zhang, Ying E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293007/
https://www.ncbi.nlm.nih.gov/pubmed/22204598
http://dx.doi.org/10.1186/2045-3701-1-43