Gene silencing of IL-12 in dendritic cells inhibits autoimmune arthritis

BACKGROUND: We have previously demonstrated that immune modulation can be accomplished by administration of gene silenced dendritic cells (DC) using siRNA. In this study, we demonstrate the therapeutic utilization of shRNA-modified DC as an antigen-specific tolerogenic vaccine strategy for autoimmun...

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Detalles Bibliográficos
Autores principales: Li, Rong, Zheng, Xiufen, Popov, Igor, Zhang, Xusheng, Wang, Hongmei, Suzuki, Motohiko, De Necochea-Campion, Rosalia, French, Peter W, Chen, Di, Siu, Leo, Koos, David, Inman, Robert D, Min, Wei-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293054/
https://www.ncbi.nlm.nih.gov/pubmed/22289162
http://dx.doi.org/10.1186/1479-5876-10-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293054/
https://www.ncbi.nlm.nih.gov/pubmed/22289162
http://dx.doi.org/10.1186/1479-5876-10-19

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