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Computational analysis of pathogen-borne metallo β-lactamases reveals discriminating structural features between B1 types

BACKGROUND: Genes conferring antibiotic resistance to groups of bacterial pathogens are cause for considerable concern, as many once-reliable antibiotics continue to see a reduction in efficacy. The recent discovery of the metallo β-lactamase blaNDM-1 gene, which appears to grant antibiotic resistan...

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Detalles Bibliográficos
Autores principales: Cadag, Eithon, Vitalis, Elizabeth, Lennox, Kristin P, Zhou, Carol L Ecale, Zemla, Adam T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293060/
https://www.ncbi.nlm.nih.gov/pubmed/22333139
http://dx.doi.org/10.1186/1756-0500-5-96