Selection of recombinant MVA by rescue of the essential D4R gene

Modified vaccinia virus Ankara (MVA) has become a promising vaccine vector due to its immunogenicity and its proven safety in humans. As a general approach for stringent and rapid selection of recombinant MVA, we assessed marker rescue of the essential viral D4R gene in an engineered deletion mutant...

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Detalles Bibliográficos
Autores principales: Ricci, Patricia S, Schäfer, Birgit, Kreil, Thomas R, Falkner, Falko G, Holzer, Georg W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293099/
https://www.ncbi.nlm.nih.gov/pubmed/22152060
http://dx.doi.org/10.1186/1743-422X-8-529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293099/
https://www.ncbi.nlm.nih.gov/pubmed/22152060
http://dx.doi.org/10.1186/1743-422X-8-529

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