Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives

Atorvastatin calcium, a lipid-lowering drug, is much less bioavailable because of reduced solubility in acidic media. Multiple-unit floating microcapsules of Atorvastatin calcium (ATC) were developed to expand the gastric residence time of the drug, as ATC has maximum rate of absorption in the upper...

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Detalles Bibliográficos
Autores principales: Khan, Furquan Nazimuddin, Dehghan, Mohamed Hassan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293352/
https://www.ncbi.nlm.nih.gov/pubmed/22396916
http://dx.doi.org/10.3797/scipharm.1104-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293352/
https://www.ncbi.nlm.nih.gov/pubmed/22396916
http://dx.doi.org/10.3797/scipharm.1104-26

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