Cargando…

Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives

Atorvastatin calcium, a lipid-lowering drug, is much less bioavailable because of reduced solubility in acidic media. Multiple-unit floating microcapsules of Atorvastatin calcium (ATC) were developed to expand the gastric residence time of the drug, as ATC has maximum rate of absorption in the upper...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Furquan Nazimuddin, Dehghan, Mohamed Hassan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293352/ https://www.ncbi.nlm.nih.gov/pubmed/22396916 http://dx.doi.org/10.3797/scipharm.1104-26

Ejemplares similares

Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization
por: Al-Kazemi, Reham, et al.
Publicado: (2019)

Comments on "Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization"
por: Emami, Shahram, et al.
Publicado: (2021)

Atorvastatin solid dispersion for bioavailability enhancement
por: Shamsuddin,, et al.
Publicado: (2016)

Cinnamaldehyde microcapsules enhance bioavailability and regulate intestinal flora in mice
por: Xiao, Ying, et al.
Publicado: (2022)

Editorial: Persistent endeavors for the enhancement of dissolution and oral bioavailability
por: Wu, Wei, et al.
Publicado: (2019)

Dissolution Improvement of Atorvastatin Calcium using Modified Locust Bean Gum by the Solid Dispersion Technique
por: Panghal, Dharmila, et al.
Publicado: (2014)

Spray-Dried Amorphous Solid Dispersions of Atorvastatin Calcium for Improved Supersaturation and Oral Bioavailability
por: Kwon, Jaewook, et al.
Publicado: (2019)

Optimized zein nanospheres for improved oral bioavailability of atorvastatin
por: Hashem, Fahima M, et al.
Publicado: (2015)

In vitro dissolution study of atorvastatin binary solid dispersion
por: Jahan, Rahat, et al.
Publicado: (2013)

Enhanced Dissolution and Oral Bioavailability of Piroxicam Formulations: Modulating Effect of Phospholipids
por: Mirza, Sabiruddin, et al.
Publicado: (2010)

Improved bioavailability through floating microspheres of lovastatin
por: Kumar, S., et al.
Publicado: (2011)

Enhanced Dissolution and Oral Bioavailability of Cyclosporine A: Microspheres Based on αβ-Cyclodextrins Polymers
por: Lahiani-Skiba, Malika, et al.
Publicado: (2018)

Synergistic Effect of Hydrotrope and Surfactant on Solubility and Dissolution of Atorvastatin Calcium: Screening Factorial Design Followed by Ratio Optimization
por: Patel, V. F., et al.
Publicado: (2014)

Encapsulation of erythromycin and bacitracin antibiotics into natural sporopollenin microcapsules: antibacterial, cytotoxicity, in vitro and in vivo release studies for enhanced bioavailability
por: Dyab, Amro K. F., et al.
Publicado: (2018)

Enhancement of dissolution of atorvastatin through preparation of polymeric solid dispersions using supercritical fluid technology
por: Altaani, Bashar, et al.
Publicado: (2020)

Formulation, release characteristics, and bioavailability study of gastroretentive floating matrix tablet and floating raft system of Mebeverine HCl
por: El Nabarawi, Mohamed A, et al.
Publicado: (2017)

Preparation, Characterization and Evaluation of Flavonolignan Silymarin Effervescent Floating Matrix Tablets for Enhanced Oral Bioavailability
por: Ahmad, Sher, et al.
Publicado: (2023)

Pharmaceutical Dispersion Techniques for Dissolution and Bioavailability Enhancement of Poorly Water-Soluble Drugs
por: Zhang, Xingwang, et al.
Publicado: (2018)

Application of hot melt extrusion to enhance the dissolution and oral bioavailability of oleanolic acid
por: Gao, Nannan, et al.
Publicado: (2017)

Electrosprayed Polymeric Nanospheres for Enhanced Solubility, Dissolution Rate, Oral Bioavailability and Antihyperlipidemic Activity of Bezafibrate
por: Sun, Ru, et al.
Publicado: (2020)

Modulating Drug Release from Gastric-Floating Microcapsules through Spray-Coating Layers
por: Lee, Wei Li, et al.
Publicado: (2014)

Improvement in the stability and bioavailability of pumpkin lutein using β‐cyclodextrin microcapsules
por: Shi, Zhenxia, et al.
Publicado: (2023)

Optically Controlled Dissolution Kinetics of Vaterite Microcapsules: Toward Novel Crystal Growth Strategies
por: Ushkov, Andrei, et al.
Publicado: (2023)

Custom fractional factorial designs to develop atorvastatin self-nanoemulsifying and nanosuspension delivery systems – enhancement of oral bioavailability
por: Hashem, Fahima M, et al.
Publicado: (2015)

Cefdinir Solid Dispersion Composed of Hydrophilic Polymers with Enhanced Solubility, Dissolution, and Bioavailability in Rats
por: Cho, Hyun-Jong, et al.
Publicado: (2017)

Flurbiprofen-Loaded Solid SNEDDS Preconcentrate for the Enhanced Solubility, In-Vitro Dissolution and Bioavailability in Rats
por: Kim, Rae Man, et al.
Publicado: (2018)

Formulation Development of Albendazole-Loaded Self-Microemulsifying Chewable Tablets to Enhance Dissolution and Bioavailability
por: Sawatdee, Somchai, et al.
Publicado: (2019)

Solubility and Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin: In Vitro, Ex Vivo, and In Vivo Studies
por: Rodde, Madhuri S., et al.
Publicado: (2014)

Dissolution Enhancement of Rosuvastatin Calcium by Liquisolid Compact Technique
por: Kapure, V. J., et al.
Publicado: (2013)

Systematic Development of Self-Emulsifying Drug Delivery Systems of Atorvastatin with Improved Bioavailability Potential
por: Khan, Fariba, et al.
Publicado: (2012)

Drug Resinates an Attractive Approach of Solubility Enhancement of Atorvastatin Calcium
por: Kulthe, V. V., et al.
Publicado: (2013)

Novel nanocrystal-based solid dispersion with high drug loading, enhanced dissolution, and bioavailability of andrographolide
por: Ma, Yueqin, et al.
Publicado: (2018)

Ion-triggered calcium hydroxide microcapsules for enhanced corrosion resistance of steel bars
por: Liang, Zi, et al.
Publicado: (2018)

Surface stabilized atorvastatin nanocrystals with improved bioavailability, safety and antihyperlipidemic potential
por: Sharma, Manu, et al.
Publicado: (2019)

Effects of Addition of Mannitol Crystals on the Porosity and Dissolution Rates of a Calcium Phosphate Cement
por: Vazquez, Debra, et al.
Publicado: (2010)

Preparation, Optimization, and In Vivo Evaluation of Nanoparticle-Based Formulation for Pulmonary Delivery of Anticancer Drug
por: Chishti, Nazimuddin, et al.
Publicado: (2019)

Enhancement of the dissolution rate and bioavailability of fenofibrate by a melt-adsorption method using supercritical carbon dioxide
por: Cha, Kwang-Ho, et al.
Publicado: (2012)

Formulation of Aceclofenac Tablets Using Nanosuspension as Granulating Agent: An Attempt to Enhance Dissolution Rate and Oral Bioavailability
por: Rahim, Haroon, et al.
Publicado: (2020)

Spectroscopic studies on photodegradation of atorvastatin calcium
por: Oprica, Madalina, et al.
Publicado: (2021)

Improving the Solubility, Dissolution, and Bioavailability of Metronidazole via Cocrystallization with Ethyl Gallate
por: Li, Jinhui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nf9ba3ra363q2lop8kncbnr648