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Reactive Oxygen Species Suppress Cardiac Na(V)1.5 Expression through Foxo1

Na(V)1.5 is a cardiac voltage-gated Na(+) channel αsubunit and is encoded by the SCN5a gene. The activity of this channel determines cardiac depolarization and electrical conduction. Channel defects, including mutations and decrease of channel protein levels, have been linked to the development of c...

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Detalles Bibliográficos
Autores principales:	Mao, Weike, You, Tao, Ye, Bo, Li, Xiang, Dong, Henry H., Hill, Joseph A., Li, Faqian, Xu, Haodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293505/ https://www.ncbi.nlm.nih.gov/pubmed/22400069 http://dx.doi.org/10.1371/journal.pone.0032738

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