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Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels
The cell cycle is a temporal program that regulates DNA synthesis and cell division. When we compared the codon usage of cell cycle-regulated genes with that of other genes, we discovered that there is a significant preference for non-optimal codons. Moreover, genes encoding proteins that cycle at t...
Autores principales: | Frenkel-Morgenstern, Milana, Danon, Tamar, Christian, Thomas, Igarashi, Takao, Cohen, Lydia, Hou, Ya-Ming, Jensen, Lars Juhl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293633/ https://www.ncbi.nlm.nih.gov/pubmed/22373820 http://dx.doi.org/10.1038/msb.2012.3 |
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