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UT-B-deficient mice develop renal dysfunction and structural damage

BACKGROUND: Urea transporter UT-B is the major urea transporter in erythrocytes and the descending vasa recta in the kidney. In this study, we investigated the effects of long-term UT-B deficiency on functional and structural defect in the kidney of 16-and 52-week-old UT-B-null mice. METHODS: UT-B-k...

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Detalles Bibliográficos
Autores principales: Zhou, Lei, Meng, Yan, Lei, Tianluo, Zhao, Dan, Su, Jing, Zhao, Xuejian, Yang, Baoxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293738/
https://www.ncbi.nlm.nih.gov/pubmed/22289137
http://dx.doi.org/10.1186/1471-2369-13-6