Interrelations between blood-brain barrier permeability and matrix metalloproteinases are differently affected by tissue plasminogen activator and hyperoxia in a rat model of embolic stroke

BACKGROUND: In ischemic stroke, blood-brain barrier (BBB) regulations, typically involving matrix metalloproteinases (MMPs) and inhibitors (TIMPs) as mediators, became interesting since tissue plasminogen activator (tPA)-related BBB breakdown with risk of secondary hemorrhage was considered to invol...

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Detalles Bibliográficos
Autores principales: Michalski, Dominik, Hobohm, Carsten, Weise, Christopher, Pelz, Johann, Heindl, Marita, Kamprad, Manja, Kacza, Johannes, Härtig, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293756/
https://www.ncbi.nlm.nih.gov/pubmed/22273146
http://dx.doi.org/10.1186/2045-9912-2-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293756/
https://www.ncbi.nlm.nih.gov/pubmed/22273146
http://dx.doi.org/10.1186/2045-9912-2-2

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