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Differential Contribution of the Repeats to Heparin Binding of HBHA, a Major Adhesin of Mycobacterium tuberculosis

BACKGROUND: Tuberculosis remains one of the most important causes of global mortality and morbidity, and the molecular mechanisms of the pathogenesis are still incompletely understood. Only few virulence factors of the causative agent Mycobacterium tuberculosis are known. One of them is the heparin-...

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Detalles Bibliográficos
Autores principales: Lebrun, Pierre, Raze, Dominique, Fritzinger, Bernd, Wieruszeski, Jean-Michel, Biet, Franck, Dose, Alexander, Carpentier, Mathieu, Schwarzer, Dirk, Allain, Fabrice, Lippens, Guy, Locht, Camille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293801/
https://www.ncbi.nlm.nih.gov/pubmed/22403657
http://dx.doi.org/10.1371/journal.pone.0032421