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A Genome-Wide Association Study Identifies rs2000999 as a Strong Genetic Determinant of Circulating Haptoglobin Levels

Haptoglobin is an acute phase inflammatory marker. Its main function is to bind hemoglobin released from erythrocytes to aid its elimination, and thereby haptoglobin prevents the generation of reactive oxygen species in the blood. Haptoglobin levels have been repeatedly associated with a variety of...

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Detalles Bibliográficos
Autores principales: Froguel, Philippe, Ndiaye, Ndeye Coumba, Bonnefond, Amélie, Bouatia-Naji, Nabila, Dechaume, Aurélie, Siest, Gérard, Herbeth, Bernard, Falchi, Mario, Bottolo, Leonardo, Guéant-Rodriguez, Rosa-Maria, Lecoeur, Cécile, Langlois, Michel R., Labrune, Yann, Ruokonen, Aimo, El Shamieh, Said, Stathopoulou, Maria G., Morandi, Anita, Maffeis, Claudio, Meyre, David, Delanghe, Joris R., Jacobson, Peter, Sjöström, Lars, Carlsson, Lena M. S., Walley, Andrew, Elliott, Paul, Jarvelin, Marjo-Riita, Dedoussis, George V., Visvikis-Siest, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293812/
https://www.ncbi.nlm.nih.gov/pubmed/22403646
http://dx.doi.org/10.1371/journal.pone.0032327