In Vivo Gene Knockdown in Rat Dorsal Root Ganglia Mediated by Self-Complementary Adeno-Associated Virus Serotype 5 Following Intrathecal Delivery

We report here in adult rat viral vector mediate-gene knockdown in the primary sensory neurons and the associated cellular and behavior consequences. Self-complementary adeno-associated virus serotype 5 (AAV5) was constructed to express green fluorescent protein (GFP) and a small interfering RNA (si...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Qinghao, Chou, Beverly, Fitzsimmons, Bethany, Miyanohara, Atsushi, Shubayev, Veronica, Santucci, Camila, Hefferan, Michael, Marsala, Martin, Hua, Xiao-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293818/
https://www.ncbi.nlm.nih.gov/pubmed/22403675
http://dx.doi.org/10.1371/journal.pone.0032581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293818/
https://www.ncbi.nlm.nih.gov/pubmed/22403675
http://dx.doi.org/10.1371/journal.pone.0032581

Ejemplares similares