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In Vivo Gene Knockdown in Rat Dorsal Root Ganglia Mediated by Self-Complementary Adeno-Associated Virus Serotype 5 Following Intrathecal Delivery
We report here in adult rat viral vector mediate-gene knockdown in the primary sensory neurons and the associated cellular and behavior consequences. Self-complementary adeno-associated virus serotype 5 (AAV5) was constructed to express green fluorescent protein (GFP) and a small interfering RNA (si...
Autores principales: | Xu, Qinghao, Chou, Beverly, Fitzsimmons, Bethany, Miyanohara, Atsushi, Shubayev, Veronica, Santucci, Camila, Hefferan, Michael, Marsala, Martin, Hua, Xiao-Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293818/ https://www.ncbi.nlm.nih.gov/pubmed/22403675 http://dx.doi.org/10.1371/journal.pone.0032581 |
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