Cargando…

The Impact of Point Mutations in the Human Androgen Receptor: Classification of Mutations on the Basis of Transcriptional Activity

Androgen receptor mediated signaling drives prostate cancer cell growth and survival. Mutations within the receptor occur infrequently in prostate cancer prior to hormonal therapy but become prevalent in incurable androgen independent and metastatic tumors. Despite the determining role played by the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hay, Colin W., McEwan, Iain J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293822/
https://www.ncbi.nlm.nih.gov/pubmed/22403669
http://dx.doi.org/10.1371/journal.pone.0032514