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eIF2α Kinases Regulate Development through the BzpR Transcription Factor in Dictyostelium discoideum

BACKGROUND: A major mechanism of translational regulation in response to a variety of stresses is mediated by phosphorylation of eIF2α to reduce delivery of initiator tRNAs to scanning ribosomes. For some mRNAs, often encoding a bZIP transcription factor, eIF2α phosphorylation leads to enhanced tran...

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Detalles Bibliográficos
Autores principales: Singleton, Charles K., Xiong, Yanhua, Kirsten, Janet H., Pendleton, Kelsey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293825/
https://www.ncbi.nlm.nih.gov/pubmed/22403666
http://dx.doi.org/10.1371/journal.pone.0032500