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Evidence for the Contribution of the Hemozoin Synthesis Pathway of the Murine Plasmodium yoelii to the Resistance to Artemisinin-Related Drugs

Plasmodium falciparum malaria is a major global health problem, causing approximately 780,000 deaths each year. In response to the spreading of P. falciparum drug resistance, WHO recommended in 2001 to use artemisinin derivatives in combination with a partner drug (called ACT) as first-line treatmen...

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Detalles Bibliográficos
Autores principales: Witkowski, Benoit, Lelièvre, Joel, Nicolau-Travers, Marie-Laure, Iriart, Xavier, Njomnang Soh, Patrice, Bousejra-ElGarah, Fatima, Meunier, Bernard, Berry, Antoine, Benoit-Vical, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293827/
https://www.ncbi.nlm.nih.gov/pubmed/22403683
http://dx.doi.org/10.1371/journal.pone.0032620