Biophysical Property and Broad Anti-HIV Activity of Albuvirtide, a 3-Maleimimidopropionic Acid-Modified Peptide Fusion Inhibitor

Albuvirtide (ABT) is a 3-maleimimidopropionic acid (MPA)-modified peptide HIV fusion inhibitor that can irreversibly conjugate to serum albumin. Previous studies demonstrated its in vivo long half-life and potent anti-HIV activity. Here, we focused to characterize its biophysical properties and eval...

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Detalles Bibliográficos
Autores principales: Chong, Huihui, Yao, Xue, Zhang, Chao, Cai, Lifeng, Cui, Sheng, Wang, Youchun, He, Yuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293837/
https://www.ncbi.nlm.nih.gov/pubmed/22403678
http://dx.doi.org/10.1371/journal.pone.0032599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293837/
https://www.ncbi.nlm.nih.gov/pubmed/22403678
http://dx.doi.org/10.1371/journal.pone.0032599

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