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Effects of Deletion of Macrophage ABCA7 on Lipid Metabolism and the Development of Atherosclerosis in the Presence and Absence of ABCA1

ABCA7, a close relative of ABCA1 which facilitates cholesterol efflux to lipid-poor apoproteins, has been implicated in macrophage lipid efflux and clearance of apoptotic cells in in vitro studies. In the current study, we investigated the in vivo effects of macrophage ABCA7 deficiency on lipid meta...

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Detalles Bibliográficos
Autores principales: Meurs, Illiana, Calpe-Berdiel, Laura, Habets, Kim L. L., Zhao, Ying, Korporaal, Suzanne J. A., Mommaas, A. Mieke, Josselin, Emmanuelle, Hildebrand, Reeni B., Ye, Dan, Out, Ruud, Kuiper, Johan, Van Berkel, Theo J. C., Chimini, Giovanna, Van Eck, Miranda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293875/
https://www.ncbi.nlm.nih.gov/pubmed/22403608
http://dx.doi.org/10.1371/journal.pone.0030984