Single Cycle Structure-Based Humanization of an Anti-Nerve Growth Factor Therapeutic Antibody

Most forms of chronic pain are inadequately treated by present therapeutic options. Compelling evidence has accumulated, demonstrating that Nerve Growth Factor (NGF) is a key modulator of inflammatory and nociceptive responses, and is a promising target for the treatment of human pathologies linked...

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Detalles Bibliográficos
Autores principales: Covaceuszach, Sonia, Marinelli, Sara, Krastanova, Ivet, Ugolini, Gabriele, Pavone, Flaminia, Lamba, Doriano, Cattaneo, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293900/
https://www.ncbi.nlm.nih.gov/pubmed/22403636
http://dx.doi.org/10.1371/journal.pone.0032212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293900/
https://www.ncbi.nlm.nih.gov/pubmed/22403636
http://dx.doi.org/10.1371/journal.pone.0032212

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