Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)–calcineurin–NFAT signaling

In hippocampal neurons, the scaffold protein AKAP79 recruits the phosphatase calcineurin to L-type Ca(2+) channels, and couples Ca(2+) influx to activation of calcineurin and of its substrate, the transcription factor NFAT. Here we show that an IAIIIT anchoring site in human AKAP79 binds the same su...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Huiming, Pink, Matthew D., Murphy, Jonathan G., Stein, Alexander, Dell'Acqua, Mark L., Hogan, Patrick G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294036/
https://www.ncbi.nlm.nih.gov/pubmed/22343722
http://dx.doi.org/10.1038/nsmb.2238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294036/
https://www.ncbi.nlm.nih.gov/pubmed/22343722
http://dx.doi.org/10.1038/nsmb.2238

Ejemplares similares