The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer

BACKGROUND: Spy1 is a novel 'cyclin-like' activator of the G1/S transition capable of enhancing cell proliferation as well as inhibiting apoptosis. Spy1 protein levels are tightly regulated during normal mammary development and forced overexpression in mammary mouse models accelerates mamm...

Descripción completa

Detalles Bibliográficos
Autores principales: Al Sorkhy, Mohammad, Ferraiuolo, Rosa-Maria, Jalili, Espanta, Malysa, Agnes, Fratiloiu, Andreea R, Sloane, Bonnie F, Porter, Lisa A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294245/
https://www.ncbi.nlm.nih.gov/pubmed/22280365
http://dx.doi.org/10.1186/1471-2407-12-45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294245/
https://www.ncbi.nlm.nih.gov/pubmed/22280365
http://dx.doi.org/10.1186/1471-2407-12-45

Ejemplares similares