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An Automated Method to Quantify Microglia Morphology and Application to Monitor Activation State Longitudinally In Vivo

Microglia are specialized immune cells of the brain. Upon insult, microglia initiate a cascade of cellular responses including a characteristic change in cell morphology. To study the dynamics of microglia immune response in situ, we developed an automated image analysis method that enables the quan...

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Detalles Bibliográficos
Autores principales: Kozlowski, Cleopatra, Weimer, Robby M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294422/
https://www.ncbi.nlm.nih.gov/pubmed/22457705
http://dx.doi.org/10.1371/journal.pone.0031814