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Solution Structure of Kurtoxin: A Gating Modifier Selective for Cav3 Voltage-Gated Ca(2+) Channels

[Image: see text] Kurtoxin is a 63-amino acid polypeptide isolated from the venom of the South African scorpion Parabuthus transvaalicus. It is the first and only peptide ligand known to interact with Cav3 (T-type) voltage-gated Ca(2+) channels with high affinity and to modify the voltage-dependent...

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Detalles Bibliográficos
Autores principales: Lee, Chul Won, Bae, Chanhyung, Lee, Jaeho, Ryu, Jae Ha, Kim, Ha Hyung, Kohno, Toshiyuki, Swartz, Kenton J., Kim, Jae Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295331/
https://www.ncbi.nlm.nih.gov/pubmed/22329781
http://dx.doi.org/10.1021/bi201633j