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Solution Structure of Kurtoxin: A Gating Modifier Selective for Cav3 Voltage-Gated Ca(2+) Channels
[Image: see text] Kurtoxin is a 63-amino acid polypeptide isolated from the venom of the South African scorpion Parabuthus transvaalicus. It is the first and only peptide ligand known to interact with Cav3 (T-type) voltage-gated Ca(2+) channels with high affinity and to modify the voltage-dependent...
Autores principales: | Lee, Chul Won, Bae, Chanhyung, Lee, Jaeho, Ryu, Jae Ha, Kim, Ha Hyung, Kohno, Toshiyuki, Swartz, Kenton J., Kim, Jae Il |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2012
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295331/ https://www.ncbi.nlm.nih.gov/pubmed/22329781 http://dx.doi.org/10.1021/bi201633j |
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