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Endothelial-monocyte activating polypeptide II disrupts alveolar epithelial type II to type I cell transdifferentiation

BACKGROUND: Distal alveolar morphogenesis is marked by differentiation of alveolar type (AT)-II to AT-I cells that give rise to the primary site of gas exchange, the alveolar/vascular interface. Endothelial-Monocyte Activating Polypeptide (EMAP) II, an endogenous protein with anti-angiogenic propert...

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Detalles Bibliográficos
Autores principales: Chen, Yao, Legan, Susan K, Mahan, Anne, Thornton, Janet, Xu, Haiming, Schwarz, Margaret A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295640/
https://www.ncbi.nlm.nih.gov/pubmed/22214516
http://dx.doi.org/10.1186/1465-9921-13-1