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Application and removal of polyanionic microbicide compounds enhances subsequent infection by HIV-1

BACKGROUND: Continued efforts are being directed toward the development of microbicides that will be used to reduce or eliminate the risk of HIV-1 sexual transmission. Unfortunately, clinical trials involving polyanion-containing microbicide formulations, including Carraguard (λ-carrageenan [LC]) an...

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Detalles Bibliográficos
Autores principales: Pirrone, Vanessa, Passic, Shendra, Wigdahl, Brian, Krebs, Fred C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295645/
https://www.ncbi.nlm.nih.gov/pubmed/22281044
http://dx.doi.org/10.1186/1743-422X-9-33