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Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties

BACKGROUND: The V3 loop of the glycoprotein gp120 of HIV-1 plays an important role in viral entry into cells by utilizing as coreceptor CCR5 or CXCR4, and is implicated in the phenotypic tropisms of HIV viruses. It has been hypothesized that the interaction between the V3 loop and CCR5 or CXCR4 is m...

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Detalles Bibliográficos
Autores principales: López de Victoria, Aliana, Kieslich, Chris A, Rizos, Apostolos K, Krambovitis, Elias, Morikis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295656/
https://www.ncbi.nlm.nih.gov/pubmed/22313935
http://dx.doi.org/10.1186/2046-1682-5-3