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Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway

ΒACKGROUND: The methylotrophic yeast Pichia pastoris has become an important host organism for recombinant protein production and is able to use methanol as a sole carbon source. The methanol utilization pathway describes all the catalytic reactions, which happen during methanol metabolism. Despite...

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Detalles Bibliográficos
Autores principales: Krainer, Florian W, Dietzsch, Christian, Hajek, Tanja, Herwig, Christoph, Spadiut, Oliver, Glieder, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295664/
https://www.ncbi.nlm.nih.gov/pubmed/22330134
http://dx.doi.org/10.1186/1475-2859-11-22