Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR

BACKGROUND: In a previous genome-wide analysis of FXR binding to hepatic chromatin, we noticed that an extra nuclear receptor (NR) half-site was co-enriched close to the FXR binding IR-1 elements and we provided limited support that the monomeric LRH-1 receptor that binds to NR half-sites might func...

Descripción completa

Detalles Bibliográficos
Autores principales: Chong, Hansook Kim, Biesinger, Jacob, Seo, Young-Kyo, Xie, Xiaohui, Osborne, Timothy F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295688/
https://www.ncbi.nlm.nih.gov/pubmed/22296850
http://dx.doi.org/10.1186/1471-2164-13-51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295688/
https://www.ncbi.nlm.nih.gov/pubmed/22296850
http://dx.doi.org/10.1186/1471-2164-13-51

Ejemplares similares