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Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages

BACKGROUND: The liver X receptors (LXRs) are oxysterol sensing nuclear receptors with multiple effects on metabolism and immune cells. However, the complete genome-wide cistrome of LXR in cells of human origin has not yet been provided. RESULTS: We performed ChIP-seq in phorbol myristate acetate-dif...

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Detalles Bibliográficos
Autores principales: Pehkonen, Petri, Welter-Stahl, Lynn, Diwo, Janine, Ryynänen, Jussi, Wienecke-Baldacchino, Anke, Heikkinen, Sami, Treuter, Eckardt, Steffensen, Knut R, Carlberg, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295715/
https://www.ncbi.nlm.nih.gov/pubmed/22292898
http://dx.doi.org/10.1186/1471-2164-13-50