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Potentially Functional Variants of PLCE1 Identified by GWASs Contribute to Gastric Adenocarcinoma Susceptibility in an Eastern Chinese Population

BACKGROUND: Recent genome-wide association studies (GWAS) have found a single nucleotide polymorphism (SNP, rs2274223 A>G) in PLCE1 to be associated with risk of gastric adenocarcinoma. In the present study, we validated this finding and also explored the risk associated with another unreported p...

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Detalles Bibliográficos
Autores principales: Wang, Mengyun, Zhang, Ruoxin, He, Jing, Qiu, Lixin, Li, Jin, Wang, Yanong, Sun, Menghong, Yang, Yajun, Wang, Jiucun, Yang, Jingmin, Qian, Ji, Jin, Li, Ma, Hongxia, Wei, Qingyi, Zhou, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295761/
https://www.ncbi.nlm.nih.gov/pubmed/22412849
http://dx.doi.org/10.1371/journal.pone.0031932