Interactions between Amyloid-β and Hemoglobin: Implications for Amyloid Plaque Formation in Alzheimer's Disease

Accumulation of amyloid-β (Aβ) peptides in the brain is one of the central pathogenic events in Alzheimer's disease (AD). However, why and how Aβ aggregates within the brain of AD patients remains elusive. Previously, we demonstrated hemoglobin (Hb) binds to Aβ and co-localizes with the plaque...

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Detalles Bibliográficos
Autores principales: Chuang, Jia-Ying, Lee, Chu-Wan, Shih, Yao-Hsiang, Yang, Tingting, Yu, Lung, Kuo, Yu-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295782/
https://www.ncbi.nlm.nih.gov/pubmed/22412990
http://dx.doi.org/10.1371/journal.pone.0033120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295782/
https://www.ncbi.nlm.nih.gov/pubmed/22412990
http://dx.doi.org/10.1371/journal.pone.0033120

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