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Persistent Humoral Immune Responses in the CNS Limit Recovery of Reactivated Murine Cytomegalovirus

BACKGROUND: Experimental infection of the mouse brain with murine CMV (MCMV) elicits neuroimmune responses that terminate acute infection while simultaneously preventing extensive bystander damage. Previous studies have determined that CD8(+) T lymphocytes are required to restrict acute, productive...

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Detalles Bibliográficos
Autores principales: Mutnal, Manohar B., Hu, Shuxian, Lokensgard, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295797/
https://www.ncbi.nlm.nih.gov/pubmed/22412996
http://dx.doi.org/10.1371/journal.pone.0033143