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Glutathione Peroxidase-1 Primes Pro-Inflammatory Cytokine Production after LPS Challenge In Vivo

Reactive oxygen species produced during the innate immune response to LPS are important agents of anti-pathogen defence but may also cause oxidative lung damage. Glutathione peroxidase-1 (gpx-1) is an anti-oxidant enzyme that may protect lungs from such damage. We assessed the in vivo importance of...

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Detalles Bibliográficos
Autores principales: Bozinovski, Steven, Seow, Huei Jiunn, Crack, Peter J., Anderson, Gary P., Vlahos, Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295802/
https://www.ncbi.nlm.nih.gov/pubmed/22412999
http://dx.doi.org/10.1371/journal.pone.0033172